| NUKLEONIKA 1993, 38(1):31-45
FREQUENCY AND INTERCELLULAR DISTRIBUTION OF CHROMOSOME
ABERRATIONS IN HUMAN LYMPHOCYTES AFTER HOMOGENEOUS
AND SIMULATED PARTIAL IRRADIATION WITH 14.7 MeV NEUTRONS
E. Boużyk, O. Rosiek, T. Zółtowski
Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland
Chromosome aberration frequencies and distributions were analyzed in lymphocytes from human blood samples
irradiated with 14.7 MeV neutrons (0.235-2.7 Gy). The exposure was either uniform or simulated partial
(1:1 mixed irradiated and unirradiated blood). Unstable aberrations were scored in cells in the first
division after phytohaemagglutinin stimulation. The dose effect curve fitted the linear-quadratic equation:
y = 0.0003 + 0.2589(±0.009)D + 0.053(± 0.009)D2.
Intercellular distribution was the Neyman's type A or negative binomial distribution. Parameters of these
functions significantly decreased in lymphocytes after simulated partial exposure, as compared to
homogeneous exposure.
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