| NUKLEONIKA 2002, 47(Supplement 1):s37-s42
INTRINSIC DEUTERIUM ISOTOPE EFFECTS ON NMR CHEMICAL SHIFTS OF HYDROGEN BONDED SYSTEMSPoul E. Hansen Department of Life Sciences and Chemistry, Roskilde University, P.O. Box 260, DK-4000 Roskilde, Denmark This mini review describes intrinsic deuterium isotope effects on 13C chemical shifts of rigid hydrogen bonded compounds primarily in solution. The steric effects of intramolecularly hydrogen bonded compounds are dissected into different bond interactions leading either to steric compression or to steric twist. One-bond isotope effects involving CH(D) bonds are analyzed in terms of substituent effects and the question is raised whether isotope effects can be useful in the study of CH-hydrogen bonds. Close X |