| NUKLEONIKA 2004, 49(Supplement 1):s43-s45
APPLICATION OF PROBIOTICS IN THE XENOBIOTIC DETOXIFICATION THERAPYPawel L. Urban1, Robert T. Kuthan2 1 Isotope Laboratory, Faculty of Biology, Warsaw University, 1 Miecznikowa Str., PL-02-096 Warsaw, Poland 2 2 Plant Pathogenesis Group, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 5a Pawińskiego Str., 02-106 Warsaw, Poland Many applications of probiotics have been described to date. In this paper, it is hypothesized that probiotic microorganisms can also be used to decrease the xenobiotics intake in humans. The use of probiotic bacteriae (e.g. strains of Lactobacillus sp. and Bifidobacterium sp.) and yeasts (Saccharomyces sp.) gives the opportunity for detoxification of various elements and compounds, considered as contaminants, directly in the lumen of human intestine. Some of these microorganisms are known to accumulate cesium, strontium and heavy metals to a great extent and also bind mycotoxins. Certainly, during the up-coming years, their native or genetically modified strains will be a part of treatment protocols in detoxification therapy. The utilization of probiotics, in the both therapy and nutrition of people living in the countries suffering from high food contamination, could result in the reduction of annual xenobiotic dose to be incorporated in their organisms. Close X |