| NUKLEONIKA 2006, 51(Supplement 2):s13-s16
SYNTHESIS OF RING LABELED [1'-14C]-L-TYROSINERyszard Kański, Wojciech Augustyniak, Marianna Kańska i>Department of Chemistry, University of Warsaw, 1 Pasteura Str., 02-093 Warsaw, Poland The synthesis of specifically ring labeled isotopomer of L-tyrosine, (l-Tyr), using chemical and enzymatic methods is reported. The carbon-14 labeled [1’-14C]-L-Tyr has been synthesized by a 6-step conversion of [2-14C]-malonic acid into [4’-14C]-phenol and its subsequent condensation with S-methyl-L-cysteine using enzyme tyrosine phenol lyase from Citrobacter freundii. Close X |