| NUKLEONIKA 2011, 56(4):259-262
ROUTINE SIMULTANEOUS PRODUCTION OF NO-CARRIER-ADDED
HIGH PURITY 64Cu AND 67Ga
Abdul H. Al Rayyes, Yasser Ailouti
Cyclotron Division, Chemistry Department, Atomic Energy Commission of Syria,
P. O. Box 6091, Damascus, Syria,
A routine production method of no-carrier-added 64Cu was performed. A copper target support is electroplated by gold then an optimized thickness of enriched 68Zn layer is deposited. The 68Zn target was bombarded with a 23.5 MeV and 250 ľA proton beam, generating the main nuclear reactions 68Zn(p,2n)67Ga and 68Zn(p,alpha n)64Cu. A semi-automated separation method using a chromatographic column system was developed for 64CuCl2 production. A 600 mCi batch of 64Cu is produced at the end of separation and purification chemistry. The radionuclidic purity of 64Cu was > 98% as required by the United States and European Pharmacopoeias. Radiochemical purity and activity concentration is suitable for labeling different ligands to produce diagnostic and therapeutic radiopharmaceuticals.
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