| NUKLEONIKA 2011, 56(4):269-276
PRODUCTION OF 18F BY PROTON IRRADIATION
OF C6H6NF AND C6H5NF2
Emil Běták1,2, Renata Mikołajczak3, Joanna Staniszewska3, Stefan Mikołajewski4, Edward Rurarz4, Jolanta Wojtkowska4
1 Institute of Physics, Slovak Academy of Sciences, 84511 Bratislava, Slovakia
2 Faculty of Philosophy and Science, Silesian University, 74601 Opava, Czech Republic
3 Institute of Atomic Energy POLATOM, Radioisotope Centre, 05-400 Otwock/Świerk, Poland
4 The Andrzej Sołtan Institute for Nuclear Studies, 05-400 Otwock/Świerk, Poland
Fluorine-18 can be produced directly by the (p,pn) reaction and also indirectly by the (p,2n) reaction on the 19F target. The overall cross section for both routes is 108 ± 20 mb at 22.5 ± 2.5 MeV. In this work, we obtained 18F, using 25 MeV protons on 2-fluoroaniline and 2,4-difluoroaniline targets. The chemical separation yield was 46 ± 7% and 47 ± 12% for 2-fluoroaniline and 2,4-difluoroaniline, respectively. Low-current 1 h irradiations led to 90 µCi of 18F produced from 2-fluoroaniline bombarded with a 70 nA beam (in good agreement with the theoretical value, 96 µCi) and to 76 µCi of 18F in case of 2,4-difluoroaniline and a 33 nA beam (prediction 85 µCi). Both values are close to the thick target result reported by Dmitriev and Molin for 22 MeV protons.
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