| NUKLEONIKA 2012, 57(3):407-410
ASSESSMENT OF THE STAFF ABSORBED DOSE RELATED
TO CYCLOTRON OPERATION AND SERVICE IN THE PRODUCTION
OF 18F RADIOPHARMACEUTICALS
Seyed M. Sadat-Eshkevar1, Alireza Karimian2, Mohammad Mirzaii3
1 Department of Nuclear Engineering, Faculty of Advanced Sciences and Technologies,
University of Isfahan, Isfahan, Iran
2 Department of Biomedical Engineering, Faculty of Engineering,
University of Isfahan, Postal code: 81746-73441, Isfahan, Iran
3 Agricultural, Medical and Industrial Research Schools (AMIRS), NSTRI, Karaj, Iran
Cyclotron accelerators are used to produce medical radioisotopes. One of the most important problems which may be encountered is malfunction of a part of the target or beam line which requires stopping of the bombardment and making a repair. The decision about doing the repair depends on the whole body dose rate in a target room. In this work, dosimetric conditions related to the production of 18FDG radiopharmaceutical were simulated by the Monte Carlo (MC) method. Independently, the dose rates were measured by 7 ICRU spherical body phantoms placed inside the liquid target room and the maze of the cyclotron. The radiation dose rate inside the target room depends on the duration of the bombardment and the time passed after stopping the bombardment. The correlation between duration of the bombardment and required time after stopping the bombardment to reach the absorbed dose rate less than 25 µSv/h, was calculated for the presence and absence of the irradiated target. The results showed that the repair can be started immediately after stopping of the proton bombardment only if the target has been ejected from the target room and the duration of bombardment has not taken more than 10 min.
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